ASXL1 Break Apart FISH Probe
Our ASXL1 Break Apart FISH Probe can be used to detect a rearrangement of the ASXL1 gene. The probe comes labeled in green and orange, and you may also choose to customize the probe to meet your needs.
Probe Details:
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASXL1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASXL1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ASXL1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: ASXL1
Gene Name: Additional Sex Combs Like 1, Transcriptional Regulator
Chromosome: CHR20: 30946146-31027122
Locus: 20q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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