MED12 FISH Probe
Empire Genomics has developed a MED12 FISH Probe which can be used to detect MED12 gene aneusomy. The probe comes labeled in Green, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED12-20-GR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED12-20-GO | 20 (40 μL) | 200 μL |
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| MED12-20-AQ | 20 (40 μL) | 200 μL |
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| MED12-20-RE | 20 (40 μL) | 200 μL |
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| MED12-20-OR | 20 (40 μL) | 200 μL |
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Gene Summary
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]
Gene Details
Gene Symbol: MED12
Gene Name: Mediator Complex Subunit 12
Chromosome: CHRX: 70338405-70362304
Locus: Xq13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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