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PDCD1 FISH Probe

Our PDCD1 probe is used to detect PDCD1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.  

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PDCD1-20-OR  (Standard Design) 20 (40 μL) 200 μL
PDCD1-20-GO 20 (40 μL) 200 μL
PDCD1-20-GR 20 (40 μL) 200 μL
PDCD1-20-AQ 20 (40 μL) 200 μL
PDCD1-20-RE 20 (40 μL) 200 μL

Gene Summary

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PDCD1

Gene Name: Programmed Cell Death 1

Chromosome: CHR2: 242792032-242801058

Locus: 2q37.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cancer that’s challenging to distinguish from lupus panniculitis (LP). Few studies have been conducted on the genetic and molecular development of the disease. This team performed whole-exome sequencing on 4 SPTCLs and 1 systemic T-cell lymphoma, along with 2 cases of LP. They also used targeted sequencing to analyze 41 genes (with known implications across hematolyhpoid malignancies) on 5 additional SPTCL biopsies. Empire Genomics’ PDCD1 and PIK3CD FISH probes were used to detect copy number variants in the 2 genes, which are abnormalities associated with lymphoma but not LP.