RUNX1-USP42 Fusion FISH Probe
The RUNX1-USP42 Fusion FISH Probe is used to confirm a fusion of the RUNX1 and USP42 genes. The fusion of the RUNX1 and USP42 genes has been associated with acute myeloid leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads. The typical turnaround time for this product is 10-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RUNX1-USP42-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RUNX1-USP42-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RUNX1
Gene Name: Runt Related Transcription Factor 1
Chromosome: CHR21: 36160097-36421595
Locus: 21q22.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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