AR FISH Probe
Empire Genomics' AR probe is designed to detect AR amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| AR-20-BIO | 20 (40 μL) | 200 μL |
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| AR-20-DNP | 20 (40 μL) | 200 μL | ||
| AR-20-RE | 20 (40 μL) | 200 μL |
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| AR-20-AQ | 20 (40 μL) | 200 μL |
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| AR-20-DIG | 20 (40 μL) | 200 μL |
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| AR-20-GR | 20 (40 μL) | 200 μL |
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| AR-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
Gene Details
Gene Symbol: AR
Gene Name: Androgen Receptor
Chromosome: CHRX: 66763873-66944119
Locus: Xq12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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