PDL1/Con9 FISH Probe

PD-L1 is a ligand that binds to the target receptor PD-1. The interaction of these proteins acts as a checkpoint and can protect a tumor cell from being labeled as a threat. Abnormalities in the PD-L1 gene in terms of its genomic location, amplification, or deletion can cause a tumor cell to become unresponsive to a signal that would otherwise cause its destruction. Understanding the PD-L1 profile of a tumor cell can open up treatment options that have recently become available. The probe comes labeled in orange and green, and you may also choose to customize the probe to meet your needs.

Probe Details